Fig. 4. UPGMA trees of Cas proteins were constructed with Geneious Prime 2020.2.4. Black and gray colors indicate agreements to consensus. Cas1 and Cas2 revealed a phylogenetic pattern according to CRISPR subtypes I-E, II-C, and II-A. The accession numbers of Cas1 and Cas2 proteins were given in Table 1. (A) Phylogenetic tree and alignment of Cas1 amino acid sequences and pairwise identity is 65.9% (B) Phylogenetic tree and alignment of Cas2 amino acid sequences and pairwise identity is 59.6%.

Korean J. Microbiol. 2021;57:12-22 https://doi.org/10.7845/kjm.2021.0093

© 2021 Korean J. Microbiol.