Pseudomonas aeruginosa |
Reduction of virulence and resistance to host defense system in ptsP mutants |
? |
EINtr represses expression of QscR, which in turn controls pyocyanin production |
EIIANtr is required for biofilm inhibition in the absence of upstream phosphotransfer |
EIIANtr |
Unknown |
Legionella pneumophila |
ptsP is required for virulence gene expression in host cells |
? |
Unknown |
Salmonella enterica |
EIIANtr negatively controls SPI-1 and SPI-4 expression and thereby regulates cellular invasion |
EIIANtr |
EIIANtr controls propionate catabolism and thereby unstabilizes HilD, which regulates SPI-1 in a post-translational manner |
EIIANtr negatively controls SPI-2 expression and thereby regulates pathogenicity |
EIIANtr |
EIIANtr prevents the SsrB protein from binding to its target promoter |
EIIANtr is required for delay of virulence circuit |
EIIANtr |
EIIANtr negatively controls expression of PhoP-regulated genes |
Escherichia coli |
Increased LPS in a ptsO mutant affects biofilm formation |
NPr |
Dephosphorylated NPr interacts specifically with LpxD |
Hypersensitive phenotype of the ptsP mutant to cellular membrane stress |
NPr |
Unknown |