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Genome sequence of Actinomyces georgiae KHUD_A1 isolated from dental plaque of Korean elderly woman
Korean J. Microbiol 2019;55(1):74-76
Published online March 31, 2019
© 2019 The Microbiological Society of Korea.

Ji-Hoi Moon1,2, Seung-Yun Shin3, Won Young Hong1, Eun-Young Jang4, Seok Bin Yang1, Jae-In Ryu5, Jin-Yong Lee1*, and Jae-Hyung Lee1,2,6*

1Department of Maxillofacial Biomedical Engineering, School of Dentistry, 2Department of Life and Nanopharmaceutical Sciences, 3Department of Periodontology, School of Dentistry, 4Department of Dentistry, Graduate School, 5Department of Preventive Dentistry, School of Dentistry, 6Kyung Hee Medical Science Institute, Kyung Hee University, Seoul 02447, Republic of Korea
Correspondence to: (J.Y. Lee) E-mail: ljinyong@khu.ac.kr; Tel.: +82-2-961-9544; Fax: +82-2-962-0598 /
(J.H. Lee) E-mail: jaehlee@khu.ac.kr; Tel.: +82-2-961-9290; Fax: +82-2-962-0598
Received January 2, 2019; Revised January 16, 2019; Accepted January 16, 2019.
Abstract
Gram-positive anaerobic bacilli Actinomyces spp. commonly reside on mucosal surfaces of the oropharynx, gastrointestinal tract, and urogenital tract. Here, we first report the draft genome sequence of Actinomyces georgiae KHUD_A1, isolated from dental plaque of a Korean elderly woman. The genome is 2,652,059 bp in length and has a GC content of 68.06%. The genome includes 2,242 protein-coding genes, 9 rRNAs, and 64 tRNA. We identified 157 KHUD_A1 strain-specific genes, including genes encoding CPBP family intramembrane metalloprotease, bile acid: sodium symporter family protein, Txe/YoeB family addiction module toxin and Phd/YefM family antitoxin. The sequence information of A. georgiae KHUD_A1 will help understand the general characteristics of the bacterial species and the genome diversity of the genus Actinomyces.
Keywords : Actinomyces georgiae, dental plaque, genome


March 2019, 55 (1)