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Genome sequence of Veillonella atypica KHUD-V1 isolated from a human subgingival dental plaque of periodontitis lesion
Korean J. Microbiol 2019;55(1):77-79
Published online March 31, 2019
© 2019 The Microbiological Society of Korea.

Jae-Hyung Lee1,2,3†, Seung-Yun Shin4†, Han Lee1, Seok Bin Yang1, Eun-Young Jang5, Jae-In Ryu6, Jin-Yong Lee1*, and Ji-Hoi Moon1,2*

1Department of Maxillofacial Biomedical Engineering, School of Dentistry, 2Department of Life and Nanopharmaceutical Sciences, 3Kyung Hee Medical Science Institute, 4Department of Periodontology, School of Dentistry, 5Department of Dentistry, Graduate School, 6Department of Preventive Dentistry, School of Dentistry, Kyung Hee University, Seoul 02447, Republic of Korea
Correspondence to: (J.Y. Lee) E-mail: ljinyong@khu.ac.kr; Tel.: +82-2-961-9544; Fax: +82-2-962-0598 /
(J.H. Moon) E-mail: prudence75@khu.ac.kr; Tel.: +82-2-961-0795; Fax: +82-2-962-0598
Received November 26, 2018; Revised January 10, 2019; Accepted January 22, 2019.
Abstract
Here we report the genome sequence of Veillonella atypica strain KHUD-V1 isolated from subgingival dental plaque of Korean chronic periodontitis patients. Unlike other V. atypica strains, KHUD-V1 carries two prophage regions and prophage remnants, as well as several genes homologous to prophage-associated virulence factors, such as virulence-associated protein E, a Clp protease, and a toxin-antitoxin system. The isolate and its genome sequence obtained here will aid to understand the diversity of the genome architecture of Veillonella within an evolutionary framework and the role of prophages that contribute to the genetic diversity as well as the virulence of V. atypica.
Keywords : Veillonella atypicau, genome, periodontitis, prophage


March 2019, 55 (1)