Korean Journal of Microbiology

Table. 2.

Interaction of plant fraction mixture + antimicrobial substance of strains DS381, DS518, DS620, and DS1515 in checkboard assay using broth microdilution against diverse microbes

Target organism	Fractional inhibitory concentration index (FICI)*

	Plant + DS381	Plant + DS518	Plant + DS620	Plant + DS1515
C. albicans ATCC10231	0.312	0.750	0.132	0.500
B. subtilis ATCC19659	0.500	0.750	0.375	0.625
S. aureus ATCC6538	0.375	0.500	0.500	0.625
P. aeruginosa KCTC2513	1.000	1.500	0.250	0.750
E. coli ATCC8739	0.750	0.625	0.140	0.375
E. faecalis GNUH-NCCP3788	0.560	1.000	1.000	0.560
K. pneumoniae GNUH-NCCP4159	0.625	0.500	1.000	1.000
L. monocytogenes GNUH-NCCP2868	0.500	1.000	1.000	0.560
S. epidermidis GNUH-NCCP672	0.375	0.625	0.500	0.500
M. luteus GNUH-NCCP3683	0.375	1.000	1.000	0.375
P. acnes GNUH-NCCP2876	1.000	1.000	1.000	1.000
A. flavus KACC44986	1.000	-**	1.000	1.250
A. flavus KACC45068	0.500	-	0.625	0.625
A. flavus KACC45146	0.625	-	0.500	0.625
A. awamori KCCM32316	1.000	-	1.000	0.500
A. alutaceus KCCM60421	0.500	-	0.625	1.500
A. niger ATCC16404	1.125	1.125	1.125	1.125
F. fugikuroi KACC46888	0.625	0.375	1.500	1.000
F. fugikuroi KACC48352	1.000	0.375	1.000	1.000
F. proliferatum KACC48354	1.000	0.500	1.000	1.000
F. verticillioides KACC48356	1.000	0.375	1.000	0.750

^*Total synergy (FICI ≤ 0.5), partial synergy (0.5 < FICI ≤ 0.75), independent (0.75 < FICI ≤ 2), antagonism (FICI > 2)

^**-, not tested

Korean J. Microbiol. 2020;56:19-27 https://doi.org/10.7845/kjm.2020.0004