Effects of MB-2002 on the body weight gain, food intake, and liver weight of rats fed a high-cholesterol diet
| ND | HCD | HCD + R | HCD + L | HCD + M | HCD + H | |
|---|---|---|---|---|---|---|
| Weight gain (g/day) | 6.18 ± 1.22 |
8.12 ± 0.94 | 7.97 ± 0.91 | 7.55 ± 1.38 | 8.07 ± 0.78 | 7.53 ± 1.38 |
| Food intake (g/day) | 23.68 ± 1.7 | 22.81 ± 1.62 | 23.14 ± 1.42 | 22.68 ± 1.47 | 22.97 ± 1.37 | 22.50 ± 1.24 |
| Liver weight (g) | 14.74 ± 1.90 |
30.21 ± 1.50 | 28.30 ± 2.08 | 29.74 ± 2.45 | 29.41 ± 1.95 | 26.78 ± 3.36 |
Data was expressed as mean ± SD,
ND, Normal diet; HCD, high-cholesterol diet; R, Rosuvastatin; L, MB-2002-L 1 × 108 dead cells/rat; M, MB-2002-M 1 × 109 dead cells/rat; H, MB-2002-H 1 × 1010 dead cells/rat.
a p < 0.05, b p < 0.0001 compared with the HCD.